Stem Cell R&D
About Mesenchymal Stem Cell
Stem cells are undifferentiated cells that have the ability to differentiate into various cell types and self-replicate.
Stem cells have the ability to differentiate into around 260 different types of cells that make up various tissues and organs in the human body.
Depending on their source, there are other types of stem cells besides cord blood mesenchymal stem cells,
including adult mesenchymal stem cells and embryonic mesenchymal stem cells.
- 01Cord Blood Mesenchymal Stem Cell
- Cord blood mesenchymal stem cells are derived from the blood found in the umbilical vein at the time of birth. Compared to other adult mesenchymal stem cells (such as those from fat or bone marrow), they are the youngest cells, making them easier to obtain with superior proliferative and differentiation abilities. These cells can be used in the treatment of various diseases, including neurological disorders, vascular diseases, autoimmune diseases, diabetes, and heart conditions. Additionally, the diverse cytokines and growth factors secreted by cord blood mesenchymal stem cells offer significant advantages for developing new therapies.
- 02Adult Mesenchymal Stem Cell
- Adult mesenchymal stem cells are harvested from an adult’s organs and tissues, such as fat or bone marrow. The collection process can be challenging if the donor is elderly, has genetic defects, or is affected by bacterial or viral infections. Compared to cord blood mesenchymal stem cells, adult mesenchymal stem cells have lower differentiation and proliferation capabilities, which can limit their effectiveness in treatments.
- 03Embryonic Mesenchymal Stem Cell
- Embryonic mesenchymal stem cells are derived from embryos and possess the highest differentiation and proliferation potential among stem cells. However, the lack of established methods to properly control these cells can lead to adverse effects, such as the development of cancer or teratomas. Due to ethical concerns associated with their extraction, the use of embryonic mesenchymal stem cells is largely restricted to research purposes.
| Category | Source | ||
|---|---|---|---|
| Cord Blood | Adipose Tissue, Bone Marrow, etc. | Embryos (Fertilized Eggs) | |
| Cancer Risk | None | None | Yes |
| Transplant-Related Side Effects | None | Yes | Yes |
| Clinical Application Experience | Extensive | Extensive | None |
| Ease of Acquisition | Easy | Difficult | Difficult |
| Mass Acquisition | Easy | Difficult | Difficult |
| Differentiation Ability | High | Low | Very High |
| Ethical Issues | None | None | Yes |